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I found these 2 lone cells just happen to express my cell-cell adhesion protein out of every other cells. I thought this was kinda cute. Guess what cell-cell adhesion this is 😄
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Mitosis in action. Three sequential mitotic events captured. In the last cell on the right, you can see every classical step of mitosis too. I find this so mesmerizing to watch.
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Three sequential cell division events. Only the cell's chromatin is visible (in purple). You can see every classical step of mitosis from chromatin condensation until separation in the last cell. It's like a little well coordinated dance.
For those little things that are inexplicably satisfying.
These cancer cells can exert a significant amount of force. Here, they can be seen bending and deforming the surrounding environment as they move around. The environment is called a cell-derived matrix, which composes of many fibrous proteins like collagen, fibronectin, elastin, etc.
A place for pictures and videos that are not the ordinary type of terrifying, but *oddly* terrifying.
Cancer cells exert forces when they move. These cells are cultured in a 3D environment called cell-derived matrix, and can be seen bending and deforming the fibers as they move around. They use special proteins called Integrins to grab and pull on the fibers. A collection clip.
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We all have a box like this, right? 🤣 So much buffer but so little enzyme
Welcome to r/LabRats! A space for scientists, researchers, and lab workers to share experiment fails, lab wins, and PI woes. Do you need advice, a place to vent, or just some lab-life humor? Want to share your big successes, your awesome protocols, and tricks of the trade? Join your fellow labrats. We also have a discord server!
One of the cell's largest protein complexes: The Nuclear Pore Complex (NPC). This complex sits on the nuclear membrane and controls what comes in and out of the cell's nucleus, things like RNA, proteins, even viruses. It's made up of ~1000 individual proteins. It's stunning.
For anything truly interesting as fuck
One of the cell's largest protein complexes: The Nuclear Pore Complex
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This cancer cell is so flexible, it's almost like it's dancing. Many cancer cells are master at shape shifting, allowing them to squeeze through gaps and spread to distant sites in the body. Some of your normal cells can also do this too.
A place to discuss all things biology! We welcome people and content from all related fields.
This cancer cell is so flexible, it looks like it's dancing. Many cancer cells are master of shape shifting, allowing them to squeeze through tiny gaps and spread to distant sites in the body. Some of your normal cells can also do this too.
For anything truly interesting as fuck
Direct witness of a blatant misinformation video and it blew my mind.
Welcome to r/LabRats! A space for scientists, researchers, and lab workers to share experiment fails, lab wins, and PI woes. Do you need advice, a place to vent, or just some lab-life humor? Want to share your big successes, your awesome protocols, and tricks of the trade? Join your fellow labrats. We also have a discord server!
Neutrophils use calcium signaling to recruit each other to site of infection (a process called swarming). You can visualise these calcium flashes with a special dye. There is an off switch to stop this wave from spreading out indefinitely. LHS: normal neutrophils. RHS: this off switch is damaged.
For anything truly interesting as fuck
Cancer heterogeneity: Same cell population on the same petri dish treated with the same inhibitor. One cell struggled and died while another resisted and thrived.
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Cancer heterogeneity: two cancer cells of the same population, in the same petri dish, treated with the same inhibitor. One struggled and died while the other adapted and thrived. This is due to the slight differences in the genetic makeup and gene expression between individual cancer cells.
For anything truly interesting as fuck
I just found this virus called African cassava mosaic virus that has this unique dumbbell shape. The technical term for it is a "twin incomplete icosahedral" shape. How fascinating!
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I laser ablate some cells the other day. It was so much fun 😌
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I had a field day using laser cutting cells. This technique is called laser ablation where light is focused onto a small area and essentially vaporizes that part or the whole cell as the result (yellow circle).
For those little things that are inexplicably satisfying.
In this current political climate, I feel Jerry needs to be taught a lesson.
Welcome to r/LabRats! A space for scientists, researchers, and lab workers to share experiment fails, lab wins, and PI woes. Do you need advice, a place to vent, or just some lab-life humor? Want to share your big successes, your awesome protocols, and tricks of the trade? Join your fellow labrats. We also have a discord server!
These melanoma cells have these strange vacuoles that I have never seen in any cancer cells before. They also expand through some sort of osmosis (maybe wrong but it's purely because it seems really fast, time interval is 10min). How curious?!
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The ATP Synthase. Protons flow makes the central stalk turn, this changes the conformation of the head piece which catalyses ATP formation. It can also use ATP to turn in the other direction to pump H+ instead. An example can be found on lysosomes! This animation took me way longer than I thought!
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The effects of the drug Vemurafenib on metastatic melanoma vs How the cancer learns its way to resist it.
A place for pictures and videos that are not the ordinary type of terrifying, but *oddly* terrifying.
My final post on vault particles. Because of everyone's reaction, the co-discoverer of vault particles Leonard Rome reached out to me and I asked him 6 of your burning questions. I promise you it's well worth your time!
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I'm unsure if this post will be allowed but I have done a mini interview with Leonard Rome - the co-discoverer of vault particles where I asked him 6 burning questions. I cant post the whole interview here but you can find it in my profile. I promise you it's well worth a read and very enlightening.
A place to discuss all things biology! We welcome people and content from all related fields.