A universal deep-learning model for zinc finger design enables transcription factor reprogramming
## A subreddit to discuss the intersection of computers and biology. ------ A subreddit dedicated to bioinformatics, computational genomics and systems biology.
Modulating the activity of human nociceptors with a SCN10A-promoter specific viral vector tool
/r/neuroscience is dedicated to the academic discussion of the discipline. While we welcome beginners to browse and learn, front page posts are heavily moderated and limited to academic journals and serious discussion. For a more casual option, please see our Beginner Megathread or the less-strict /r/neuro.
De novo design of luciferases using deep learning
## A subreddit to discuss the intersection of computers and biology. ------ A subreddit dedicated to bioinformatics, computational genomics and systems biology.
The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain
/r/neuroscience is dedicated to the academic discussion of the discipline. While we welcome beginners to browse and learn, front page posts are heavily moderated and limited to academic journals and serious discussion. For a more casual option, please see our Beginner Megathread or the less-strict /r/neuro.
Hereditary Alpha-Tryptasemia is Associated with Ongoing Symptoms in Individuals with Celiac Disease Despite Following a Gluten-Free Diet
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Assessing Gastrointestinal Awareness on TikTok: A Content Analysis of Colorectal Cancer, IBS, and IBD Narratives
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
From pharmacophore predictions to pharmaceutical possibilities: an integrated approach to screen M3 selective muscarinic receptor antagonist
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Bacterial Histamine as a Therapeutic Target for Abdominal Pain in Irritable Bowel Syndrome: A Literature Review
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Learning a deep language model for microbiomes: The power of large scale unlabeled microbiome data
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
The paraventricular thalamus mediates visceral pain and anxiety-like behaviors via two distinct pathways
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Causality Between Irritable Bowel Syndrome and Suicide Attempt: A Mendelian Randomization Study
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Prevalence of sucrase-isomaltase gene variants in people with and without IBS using the NIH/HGRI all-of-us database
A place to discuss Congenital Sucrase Isomaltase Deficiency (CSID) and related dietary issues.
Prevalence of sucrase-isomaltase gene variants in people with and without IBS using the NIH/HGRI all-of-us database
ibs: it's a pain
Ebastine in combination with low-dose antidepressants for refractory irritable bowel syndrome: A randomized controlled trial
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Anticholinergic agents and impaired cognitive function: is there a risk for patients with irritable bowel syndrome?
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Gastrointestinal transit abnormalities in irritable bowel syndrome and their relation to symptoms
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Optogenetic activation of the gut-brain axis in freely moving mice using a fully implantable wireless battery-free device
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
The Overlap of Allergic Disorders and Upper Gastrointestinal Symptoms: Beyond Eosinophilic Esophagitis
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
A “Janus” structured nanoclay microgel system for targeted probiotic therapy in diarrhea-predominant irritable bowel syndrome
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
HMGB1 derived from macrophages and enteric glial cells contributes to the butyrate-induced colonic hypersensitivity in mice
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
New Oral Gene Therapy Made Possible by Colorectal Cancer Findings
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
Transient colonization with Blastocystis spp. after transmission via fecal microbiota transplantation
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.
ART26.12, a novel fatty acid-binding protein 5 inhibitor, shows efficacy in multiple preclinical neuropathy models
A community dedicated strictly to the research on Irritable Bowel Syndrome (IBS) with the goal to 1) create a better definition of the disorders that together make up IBS, 2) provide a better and more comprehensive diagnostic roadmap to people with IBS and 3) provide solutions to those disorders.