Help With a Sophia Burn of Rose?

Hi. Odd request so I figured I'd come to the experts. What are your favorite burns of Rose by Sophia? I am trying to locate a particular one, it was a simple one-liner that may or may not have been about drugs or pharmaceuticals (I could have made that up) but was definitely about Rose not being very swift. I know none of this really narrows it down. Pretty sure Sophia was sitting at the kitchen table.

It's been 33 years, sorry but it's the last thing I saw my mother laugh at while she was dying, and she laughed at it uncharacteristically like a lunatic for like five straight minutes. I'm just super annoyed that I can no longer remember what it was. Not really expecting to get it but if nothing else, I figured this thread could be good for a chuckle?