Quick questions for LasVegas veterans. Should I play Vanilla ?

So I'm new to this game and before I start my game, should I install mods or go vanilla ? Or if I need to use mods what mods should I use ? Btw I would like to point out that the reason I want to use mods is that I think this game's mechanics is old enough to discomfort my eyes. otherwise I normally like to play games vanilla first.

So basically I don't want game changer mods. but I am open to your opinios.

Btw İf there is some vanilla friendly modPacks I can try them too if you recomend me one.

Thank you and sorry for my poor english