HFBA query
Hi all, so I never used heptaflurobutyric acid (HFBA) before on HPLC's but I have been told that it "stick" to the instruments and hard to get rid of off the systems.
It seems that the method used was adapted from a LC/MS-MS method to work with FLD's which I have.
Can I just replace HFBA with TFA(trifluroacetic which I know is more acidic and might quench fluroscence)? Which I know I can get off my system.
Thanks in advance for any help.