Is guanfacine likely to get better?

I've been on 1mg guanfacine for 19 days, after bouncing hard off Elvanse. I've got ADHD, ME/CFS, EDS, MCAS, PTSD, RLS, and various other things. I'm 47, a cis woman, autistic, and perimenopausal.

Meds review with the psychiatrist is tomorrow.

Side effects which have resolved, but I assume may return with a dose increase:

Heavy sedation week 1 Bradycardia week 2.

Side effects which are still here:

Constipation More abdominal pain than usual Nausea Worse sleep Possibly a Periodic Limb Movement Disorder flare (PLMD occurs during sleep so I don't know, but my Garmin thinks I'm awake for huge chunks of the night) Chills that are often waking me up Occasionally feeling depressed (I don't have depression) and with worse executive dysfunction Sexual dysfunction (not enough data yet, mind!)

Improvements: not sure there are any? I was really glad to get some executive function back after the worse days, but all I managed was some housework. I'm still struggling to read, and not sewing.

Possibly a bit less anxiety, though for the first week that could have been because I was half-asleep.

I've also started seeing a dietitian during this time, and she spotted some of my MCAS triggers right away (tomatoes, alas), so the MCAS hasn't been as bad.

Do these particular side effects resolve, or would they have by now if they were going to?

Would you normally be expecting to feel an improvement by now?

I figure I'll probably give it another month, but it depends on whether she reckons the side effects will clear up.

I was rather antsy about methylphenidate, since I felt awful on Elvanse and had no benefit at all, and in particular don't do well with my heart rate running higher. That's why I went for guanfacine second. But I understand that when it works for people, it can calm you down enough that the heart rate isn't too bad?

Thanks, all.